The transplant diagnostics market refers to the field of medicine that involves testing and analysis of organ and tissue compatibility between the donor and recipient in organ transplantation procedures. It primarily focuses on determining the compatibility of the human leukocyte antigen (HLA) system, which plays a crucial role in immune response and rejection.
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The report "Transplant Diagnostics Market by Technology (PCR, NGS, Sanger Sequencing), Product(Instrument, Reagent, Software), Application(HLA, Blood Profile, Pathogen Detection), Type (Heart, Kidney, Liver, Bone Marrow), End User, & Region - Global Forecasts to 2028", is projected to reach USD 6.8 billion by 2028 from USD 4.4 billion in 2022, at a CAGR of 7.4% during the forecast period.
Transplant diagnostics play a vital role in ensuring successful organ transplantation by assessing the degree of compatibility between the donor and recipient. These diagnostic tests help in identifying potential immune reactions, minimizing the risk of rejection, and improving overall transplant outcomes.
Key components of the transplant diagnostics market include:
· HLA Typing: Human leukocyte antigen (HLA) typing is performed to match the HLA markers between the donor and recipient. HLA typing methods include serological typing, molecular typing (such as polymerase chain reaction-based techniques), and next-generation sequencing (NGS) methods.
· Cross-Matching: Cross-matching involves testing the recipient's serum against the donor's lymphocytes or vice versa to assess compatibility and minimize the risk of hyperacute rejection.
· Serological Assays: Serological assays are used to detect antibodies in the recipient's serum against specific HLA antigens, helping to assess the risk of antibody-mediated rejection.
· Molecular Assays: Molecular assays, including polymerase chain reaction (PCR) and NGS techniques, are used for high-resolution HLA typing and to identify genetic variations associated with transplant outcomes.
· Non-HLA Testing: In addition to HLA testing, non-HLA testing may also be performed to assess other factors that influence transplant outcomes, such as cytokine gene polymorphisms, viral infections, and immunosuppressant drug monitoring.
The transplant diagnostics market has witnessed significant growth in recent years due to the increasing number of organ transplant procedures, advancements in HLA typing technologies, and the growing need for personalized medicine in transplantation. The market includes various diagnostic companies, research institutions, hospitals, and transplant centers that offer transplant diagnostic services and products.
Market Segmentation:
Molecular assay technologies segment to register a significant growth rate over the forecast period of 2022-2028
Based on Technology, molecular assay technologies are segmented to witness the highest growth during the forecast period. Molecular assay technologies are segmented into PCR-Based molecular assays and sequencing-based molecular assays. PCR-based molecular assays are further segmented into Real-time PCR, Sequence-specific primer, Sequence-specific Oligonucleotide and other PCR-based molecular assays.
Sequence-specific Oligonucleotide is growing at the highest CAGR of 9.5%.
The reagents and consumables is projected to reach USD 5,131.0 million from USD USD 3,265.2 million in 2022 with the CAGR of 7.8%.
Based on End users, the transplant diagnostic market is segmented into Hospitals and Diagnostic centers, Research & Academic Institutes and Independent reference laboratories. The Independent reference laboratories segment accounted for the largest share of the transplant diagnostic market.
North America to register major growth in the market during the forecast period
North America transplant diagnostic market is anticipated to register the highest growth over the forecast period of 2022 to 2028. North America accounted for the largest share of 45.5% of the transplant diagnostic market in 2022. This market is projected to reach USD 3.1 billion by 2028 from USD 2.0 billion in 2022, at a CAGR of 7.6% during the forecast period. North America holds 45.5% share of the total antimicrobial susceptibility testing market.
Prominent players are Becton, Dickinson and Company, Biomerieux SA, Bio-Rad Laboratories, Inc.F-Hoffman-LA-Roche, and Thermo fisher Scientific.
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